Package: paramlink2 1.0.6

Magnus Dehli Vigeland

paramlink2: Parametric Linkage Analysis

Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via 'MERLIN' (Abecasis et al. (2002) <doi:10.1038/ng786>), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. 'paramlink2' is part of the 'pedsuite' package ecosystem, presented in 'Pedigree Analysis in R' (Vigeland, 2021, ISBN:9780128244302).

Authors:Magnus Dehli Vigeland [aut, cre]

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NEWS

# Install 'paramlink2' in R:
install.packages('paramlink2', repos = c('https://magnusdv.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/magnusdv/paramlink2/issues

Datasets:
  • dominant1 - Dominant linkage analysis example

On CRAN:

5 exports 3 stars 1.26 score 12 dependencies 1 dependents 5 scripts 208 downloads

Last updated 11 days agofrom:243d57dc08. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKSep 07 2024
R-4.5-winOKSep 07 2024
R-4.5-linuxOKSep 07 2024
R-4.4-winOKSep 07 2024
R-4.4-macOKSep 07 2024
R-4.3-winOKSep 07 2024
R-4.3-macOKSep 07 2024

Exports:diseaseModellodlodPeaksmerlinLodpeakSummary

Dependencies:evaluatehighrkinship2knitrlatticeMatrixpedmutpedprobrpedtoolsquadprogxfunyaml

Readme and manuals

Help Manual

Help pageTopics
Disease models for linkage analysisdiseaseModel
Dominant linkage analysis exampledominant1
S3 methods for class 'linkres'.linkres plot.linkres points.linkres print.linkres summary.linkres
Singlepoint LOD scorelod
LOD score peakslodPeaks peakSummary
Multipoint LOD scores by MERLINmerlinLod